Expected Impacts Implementation of validated safe by design strategies including enabling their uptake and utilization by SMEs Integration of specific characteristics of advanced multi-component nanomaterials in risk assessment and safe by design strategies Recommendations on adaptation and improvement of current guidelines for exposure and hazard assessment of advanced multi-component nanomaterials Innovation capacity, market opportunities, competitiveness and growth A categorisation scheme to cluster sector-specific multi-component nanomaterials by assessing nano-specific properties in real-life environments Impact on human health, environment and regulations