September 26, 2023

Authors: G.P. Gakis, I.G. Aviziotis, C.A. Charitidis

The challenging nature of in vivo and in vitro toxicity assessment methods for ENMs, has led to emerging in silico techniques for ENM toxicity assessment, such as structure–activity relationship (SAR) models. Although such approaches have been extensively developed for the case of single-component nanomaterials, the case of multicomponent nanomaterials (MCNMs) has not been thoroughly addressed. In this paper, we present a SAR approach for the case metal and metal oxide MCNMs.

February 1, 2023

Authors: Lya Soeteman-Hernández, Carlos Felipe Blanco, Maarten Koese, Adrienne Sips, Cornelle Noorlander, Willie Peijnenburg

Technical and policy-related literature was surveyed for battery technologies and recommendations were provided for a broad SSbD approach that remains firmly grounded in Life Cycle Thinking principles. The approach integrates functional performance and sustainability aspects throughout the life cycle of materials, products and processes. It evaluates how their interactions reflect on SSbD parameters.

October 7, 2022

Authors: Sonia Cambiaso, Fabio Rasera, Giulia Rossi, Davide Bochicchio

This paper develops a transferable coarse-grained model of PDMS, compatible with the recent Martini 3 force field, using structural and thermodynamic properties as targets in the parametrization, including a vast set of experimental free energies of transfer.

May 9, 2022

Authors: Stella Stoycheva, Alex Zabeo, Lisa Pizzol, Danail Hristozov

This manuscript describes an innovative approach to socio-economic assessment of (advanced) engineered nanomaterials and nano-enabled products (NEPs) to support safe-and-sustainable-by-design (SSbD) decision making by industries in the early stages of product development.

March 1, 2022

Authors: Jacopo Cardellini, Lucrezia Caselli, Enrico Lavagna, Sebastian Salassi, Heinz Amenitsch, Martino Calamai, Costanza Montis, Giulia Rossi, Debora Berti

In this study, we address the kinetics of interaction of citrate-capped AuNP with lipid vesicles of different rigidities (gel-phase rigid membranes on one side and liquid-crystalline-phase soft membranes on the other). The formation of AuNP–lipid vesicle hybrids was monitored over different time and length scales, combining experiments and simulation.

September 7, 2021

Authors: Sebastian Salassi, Lucrezia Caselli, Jacopo Cardellini, Enrico Lavagna, Costanza Montis, Debora Berti, Giulia Rossi

Citrate capping is one of the most common strategies to achieve the colloidal stability of Au nanoparticles (NPs) with diameters ranging from a few to hundreds of nanometers. Citrate-capped Au nanoparticles (CNPs) represent a step of the synthesis of Au NPs with specific functionalities, as CNPs can be further functionalized via ligand-exchange reactions, leading to the replacement of citrate with other organic ligands.

July 9, 2021

Authors: Willie Peijnenburg, Agnes Oomen, Lya Soeteman-Hernández, Monique Groenewold, Adrienne Sips, Cornelle Noorlander, Jolinde Kettelarij, Eric Bleeker

The EU Chemicals Strategy for Sustainability is a first step to achieve the Green Deal ambition for a toxic-free environment, and ensure that chemicals are produced and used in a way that maximises their contribution to society while avoiding harm to our planet and to future generations. Advanced materials are predicted to play a pivotal role in achieving this ambition and the underlying sustainability goals, and considerable efforts are invested in designing new classes of materials.

June 21, 2021

Author: Andreas Falk

The “international network initiative on safe and sustainable nanotechnology” (INISS-nano) was formed, aiming to bring together science, industry and government from partners all over the world. The focus shall be on the collaboration in different fields pertaining to nanotechnology research in general and nano-safety research in particular.